CABAS is a freeware program devoted to fitting of linearquadratic doseresponse curves for dicentric and ringtype chromosomal aberrations as used in biological dosimetry. The procedure of fitting chromosomal data to a linearquadratic equation should be performed by the method of maximum likelihood. This method is difficult to apply because it is not implemented in the widely used, low cost statistical software packages. A further difficulty is the correct calculation of the 95% confidence interval of dose on the calibration curve. Although a number of papers have been published were the problem of proper curvefitting is discussed and different solutions are proposed, these are difficult to implement for people who have no support of a statistician. Therefore, we decided to develop a freely available tool with the help of which the user can:
A full description of CABAs can be found in: Deperas, J., M. Szłuińska, M. DeperasKaminska, A. Edwards, D. Lloyd, C. Lindholm, H. Romm, L. Roy, R. Moss, J. Morand, A Wojcik. CABAS  a freely available PC program for fitting calibration curves in chromosome aberration dosimetry. Radiation Protection Dosimetry 124:115123, 2007.
last updated: 14.12.2007 by Andrzej Wojcik 



Download HPA paper on statistical methods in biological dosimetry 


